You are not currently signed in to MyRexall. | Sign in | Register

Natural Health Products

Search or browse for information on Natural Health Products


Common Name(s)

MSM, methylsulfonylmethane

Scientific Name(s)

methylsulfonylmethane, dimethyl sulfone, sulfonylbismethane

General Information

MSM can be found naturally in small amounts in grains, fruits and vegetables, and in humans. It is also available as supplements.

How is this product usually used?

MSM is usually found in combination with supplements like glucosamine or chondroitin. It is taken orallyorallyto be taken by mouth (swallowed) (by mouth) usually with food, and it is available in different forms such as tablets and capsules.

What is this product used for?

MSM may have anti-inflammatory actions. It is used to relieve joint pain in a type of arthritis known as osteoarthritis, including osteoarthritis of the knee. Several studies have shown that when used alone or with glucosamine, MSM reduces symptoms of pain and joint movement in people with osteoarthritis. It does not appear to help with joint stiffness.

The dose ranges from 1,500 mg to 6,000 mg each day, but not to exceed 2000 mg in a single dose. MSM should be taken with food, and preferably not at bedtime.

Your health care provider may have recommended this product for other conditions. Contact a health care provider if you have questions.

What else should I be aware of?

It may take 4 weeks before you notice any improvement. If at any time your symptoms worsen, contact your health care provider.

MSM appears to be safe for most people when taken for a short period of time (3 months or less). Common side effects reported include diarrhea, nausea, bloating, indigestion, headache, insomnia, and worsening of existing allergy symptoms.

Pregnant or breast-feeding women should consult a health care practitioner before using MSM.

Before taking any new medications, including natural health products, speak to your physician, pharmacist, or other health care provider. Tell your health care provider about any natural health products you may be taking.


  1. MSM. Natural Medicines Comprehensive Database. (Accessed 3 July 2012)
  2. Health Canada. Licensed Natural Health Products. MSM (monograph). (accessed 19 March 2014)
  3. Natural Standards. MSM. Accessed 19 March 2014.

All material © 1996-2016 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.