Medications
There are several medications that are approved for managing weight and weight-related health concerns to be used, along with health behaviour changes and counselling. They are considered as part of a long-term treatment strategy, rather than a "quick fix".10
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Liraglutide (Saxenda®) and semaglutide (Wegovy®) are known as GLP-1 receptor agonists, and tirzepatide (Zepbound®) is called a GLP1/GIP agonist. All three of these medications help to regulate appetite and increase your feeling of fullness. They are given as subcutaneous (into the fat tissue) injections. You can inject them yourself or have someone help you. Common side effects include nausea, vomiting, diarrhea, and constipation.
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Setmelanotide (Imcivree®) is a unique treatment for obesity in people with a rare genetic disorder. It is also given as an injection. Side effects can include darkening of the skin, injection site reactions, nausea, and vomiting.
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There are two oral medications for weight management. Naltrexone/bupropion (Contrave®) is a combination medication that increases your feeling of fullness and helps to reduce cravings. This medication can cause nausea, constipation, headache, dry mouth, dizziness and diarrhea. Orlistat (Xenical®) helps to reduce the amount of fat that is absorbed in the body. Orlistat can cause loose, watery stools and flatulence, especially if too much fat is consumed while taking the medication.
If you and your doctor decide that medications are right for you, the choice of medication will depend on many factors, including how often it is taken (some are daily or multiple times a day, and some are weekly), whether you are comfortable with injections, other medications that you take that may conflict with certain medications or medical conditions, and the health benefits that you hope to achieve.10
While all of the medications are safe and effective ways to help you lose weight, they have different effects on metabolic health, but generally, can:10
- Lower blood pressure
- Improve cholesterol levels
- Lower blood sugar levels in people with type 2 diabetes
If you are prescribed one of these medications for weight management, it's essential to stay on track. If you stop the medication, you will likely regain weight, so reach out to your Rexall pharmacist or doctor if you are having trouble taking it or are bothered by side effects.